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Orotic acid

CAS No. 65-86-1

Orotic acid ( —— )

产品货号. M15504 CAS No. 65-86-1

乳清酸(OA)是嘧啶代谢的中间体。乳清酸(6-羧基尿嘧啶)是一种杂环化合物和酸。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
50MG ¥308 有现货
100MG ¥405 有现货
200MG ¥470 有现货
500MG ¥753 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Orotic acid
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    乳清酸(OA)是嘧啶代谢的中间体。乳清酸(6-羧基尿嘧啶)是一种杂环化合物和酸。
  • 产品描述
    Orotic acid (OA) is an intermediate in pyrimidine metabolism. Orotic acid(6-Carboxyuracil) is a heterocyclic compound and an acid.(In Vitro):Orotic acid is found in milk and dairy products, and it is converted to uridine for use in the pyrimidine salvage pathway predominantly in liver, kidney and erythrocytes.(In Vivo):Orotic acid is a marker for measurement of urea cycle disorders (UCDs), including ornithine transcarbamylase deficiency (OTCD).Orotic acid (1.0% addition to the diet; p.o. for 3-10 d) induces a development of fatty liver by day 7, and decreases purine/pyrimidine ratio of hepatic acid-soluble nucleotides by day 3.
  • 体外实验
    Orotic acid is found in milk and dairy products, and it is converted to uridine for use in the pyrimidine salvage pathway predominantly in liver, kidney and erythrocytes.
  • 体内实验
    Orotic acid is a marker for measurement of urea cycle disorders (UCDs), including ornithine transcarbamylase deficiency (OTCD).Orotic acid (1.0% addition to the diet; p.o. for 3-10 d) induces a development of fatty liver by day 7, and decreases purine/pyrimidine ratio of hepatic acid-soluble nucleotides by day 3.
  • 同义词
    ——
  • 通路
    Metabolic Enzyme/Protease
  • 靶点
    Dehydrogenase
  • 受体
    DHOase
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    65-86-1
  • 分子量
    156.1
  • 分子式
    C5H4N2O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: 2 mg/mL (12.81 mM)
  • SMILES
    OC(=O)C1=CC(=O)NC(=O)N1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Takeuchi K, et al. J Toxicol Sci. 2015;40(2):181-9
产品手册
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